Show HN: A peptide design tool for cancer vaccine https://ift.tt/39BVLFl

Show HN: A peptide design tool for cancer vaccine Dear HNers, I have coded a tool that hopefully could help oncologists to design a peptide vaccine for personalized medicine. https://ift.tt/3dxXnkF Some peptides are specific to cancers. A peptide vaccine is a way to train our body to eradicate the cells that harbor these peptides on their outer membrane. Peptide vaccines are notoriously ineffective but safe, so they could be a second line of defense against cancer after traditional drugs and therapies. A tumor develops many mutations, over time. So there is no standard medical answer. A peptide vaccine will therefore be composed of a set of peptides, which may vary over time. Because peptide vaccines can be designed very quickly, they can help respond as soon as drug resistance develops. Peptide vaccines could be a way for oncologists to distinguish themselves from their colleagues in practice, and allow them to express their know-how. This service uses its own MHC prediction service in PHP (derived from PSSMHCpan). So it is faster than NetMHCPan, but alas, it is currently hosted on a cheap VPS so it cannot take much load. I wonder if you could suggest some business model for this kind of tool? Thanks! April 3, 2021 at 11:13AM